The health ministry in Hamas-run Gaza said an Israeli strike on Saturday on a school where displaced people were sheltering killed 16 people.

The ministry, which condemned the strike as an "odious massacre", said another 50 injured were taken to hospital from Al-Jawni school at Nuseirat in central Gaza.

The Israeli military made no immediate comment when approached by AFP.

The Hamas-run government's press office said there were 7,000 people sheltering at the school.

Earlier, paramedics said 10 people, including three journalists, died in a strike on a house in Nuseirat.

The UN agency for Palestinian refugees, UNRWA, said two of its workers were killed in a strike at Al-Bureij in central Gaza. The agency has a major food warehouse in the district.

"Absolutely no place in the Gaza Strip is safe," said civil defence spokesman Mahmud Bassal.

The war began with Hamas's October 7 attack on southern Israel that resulted in the deaths of 1,195 people, mostly civilians, according to an AFP tally based on Israeli figures.

The militants also seized hostages, 116 of whom remain in Gaza including 42 the military says are dead.

In response, Israel has carried out a military offensive that has killed at least 38,098 people in Gaza, also mostly civilians, according to data from the Gaza health ministry.