A would-be suicide bomber near the mosque in Khairukhel was shot dead by local peace committee volunteers in Lakki Marwat, reported 24NewsHD TV channel on Friday.
According to local committee volunteers, the firing caused the explosive device installed in the motorcycle to explode.
Three locals were also injured in the explosion.
Friday prayers were being offered in the mosque at the time of the explosion.
After the explosion, the motorcycle and the suicide bomber caught fire.
Reporter: Malik Rehman