Artificial sweeteners may be linked to heart disease risk, study suggests
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Sweeteners are consumed by millions every day in products like diet soda, partly as a way to avoid weight gain from sugar -- but the healthiness of these substitutes has long been a matter of controversy.
Aiming to assess the heart disease risk of sweeteners, researchers at the French INSERM institute analysed the data of more than 100,000 adults in France who self-reported their diet, lifestyle and medical history between 2009-2021 as part of the NutriNet-Sante study.
Thirty-seven percent of the participants consumed artificial sweeteners, with an average intake of 42 milligrams a day -- the equivalent of one packet of sweetener or about a third of a can of diet soda.
"These results, in line with the latest WHO report published this year, do not support the use of sweeteners as a safe alternative to sugar," said INSERM's Mathilde Touvier, who coordinated the study.
An April report from the World Health Organization said that "there is no clear consensus on whether non-sugar sweeteners are effective for long-term weight loss or maintenance, or if they are linked to other long-term health effects".
However such observational studies have come under increased criticism because they cannot establish the cause of the differences they find, which could come from other sources.
Naveed Sattar, a professor of metabolic medicine at Glasgow University not involved in the sweetener study, said that it "cannot answer the question posed".
"This is because there are clearly major differences in many characteristics of people who consume artificial sweeteners compared to those who do not consume any," he said.
He called for governments to fund long-term, randomised trials "to get closer to the truth".