Novak Djokovic got off to a winning start at the Italian Open on Wednesday, advancing to the third round of the clay-court tournament in his first match since his US Open disqualification earlier this month.

The world number one, the recipient of a first round bye in Rome, eased past Italian wild card entry Salvatore Caruso 6-3, 6-2 at the Foro Italico.

Four-time Rome winner Djokovic will next play either fellow Serb Filip Krajinovic or Italian qualifier Marco Cecchinato for a place in the quarter-finals. 

Djokovic was unbeaten in 2020 before his dramatic last 16 default in New York on September 6 after he accidently struck a line judge with a ball hit in frustration.

Nine-time Rome winner Rafael Nadal will make his return to competition later on Wednesday after a six-month hiatus linked to the coronavirus pandemic.

The number two seed plays fellow Spaniard Pablo Carreno, a recent semi-finalist of the US Open, for a place in the third round. 

Sixth seeded Belgian David Goffin lost his second round match 6-2, 6-2 to Croatia's Marin Cilic in the final tune-up for the French Open in Roland Garros from September 27.