India's Serum Institute 'to invest in UK'
Johnson's Downing Street office said the £240 million ($334 million) project would include a sales office, "clinical trials, research and development and possibly manufacturing of vaccines".
SII has also begun phase one trials in the UK of a one-dose nasal vaccine for coronavirus.
Downing Street said the vaccine maker's plans were part of a wider package of trade and investment deals with India worth £1 billion that it expects to create over 6,500 jobs.
It was announced ahead of virtual talks between Johnson and Indian Prime Minister Narendra Modi on Tuesday.
With its massive population and growing economy, India has been high on London's list of trade deal targets since Britain left the European Union last year.
But a surge in Covid-19 cases has left the health system there at breaking point, forcing Johnson to shelve a planned visit this month.
Before the current wave, India was exporting tens of millions of SII-made AstraZeneca shots via through the Covax scheme supplying poorer countries.
Last month New Delhi froze exports -- including to Covax -- to prioritise jabs at home.
SII makes 60-70 million AstraZeneca doses per month, and is aiming for 100 million by July.
With its 1.3 billion people, India has become the latest hotspot of the pandemic, even as richer countries take steps towards normality with accelerating vaccination programmes.
Britain said Sunday it was sending an extra 1,000 oxygen ventilators to India, having already sent 495 oxygen concentrators, 200 ventilators and three larger production units dubbed oxygen factories.
SII, based in Pune, southeast of Mumbai, is a state-of-the-art production facility headed by 40-year-old chief executive Adar Poonawalla, scion of a pharmaceutical dynasty worth an estimated £11 billion.
Poonawalla attracted criticism for heading to London just before Britain put India on a red list of banned countries as infection rates and deaths spiralled back home.
He told The Times in an interview published on Saturday that he had joined his wife and children in Britain because highly-placed Indians were pressuring him to provide them with jabs first. "'Threats' is an understatement," he said -- although he has since announced he is heading back to India.