Banksy auctions painting for UK health service staff
"Game Changer" is a black and white depiction of a little boy playing with the doll of a nurse in a mask, near a bin with Batman and Superman toys.
It first appeared at Southampton General Hospital on England's south coast last May during the first wave of the global health crisis.
The elusive street artist penned a note to staff at the time: "Thanks for all you're doing. I hope this brightens up the place a bit, even if it's only in black and white."
Auction house Christie's said it will go on sale on March 23 and has a pre-sale estimate of between £2.5 - 3.5 million ($3.5-4.8 million, 2.9-4.1 million euros)
Katharine Arnold, Christie's co-head of post-war and contemporary art, called "Game Changer" a "universal tribute to all those fighting worldwide on the front line of this crisis".
A reproduction of the work will stay at the hospital.