Daily Covid tests, infections slide in Pakistan
NIH data shows number of critical patients goes up: EU warns antibody drugs poor against new Covid strains
December 10, 2022 11:05 AM
The number of everyday Covid-19 infections are coming down in Pakistan steadily as the country recorded only 16 more coronavirus cases with no fatality during the last 24 hours (Friday), showed the statistics released by the National Institute of Health (NIH) on Saturday morning, reported 24NewsHD TV channel.
According to the NIH data, the death toll in the country remained the same at 30,635 whereas the number of total infections now rose to 1,575,422 after adding the fresh 16 cases, the lowest in many many months.
During the last 24 hours (Friday), 5,439 tests were conducted throughout Pakistan whereas the positivity ratio stood at 0.28 percent. The number of patients in critical care was 34.
https://twitter.com/NIH_Pakistan/status/1601387847692718081
EU warns antibody drugs poor against new Covid strains
The EU's drug watchdog warned on Friday that antibody treatments for Covid are ineffective against the newest and increasingly dominant strains of the disease.
Numerous monoclonal antibodies, which are given by injection or infusion in hospital, have helped blunt the worst of the disease for at-risk or hospitalised patients.
They work by targeting the spike protein of the virus.
But the European Medicines Agency (EMA) "cautioned (they) are unlikely to be effective against emerging strains".
Lab tests showed they "are poorly effective at neutralising Omicron strains BA.4.6, BA.2.75.2 and XBB," the Amsterdam-based regulator said in a statement.
They also "do not significantly neutralise BQ.1 and BQ.1.1, which are expected to become the dominant strains in the EU in the coming weeks".
The main antibody treatments include AstraZeneca's Evusheld, Roche's Ronapreve, and GSK and Vir's Xevudy.
Antiviral treatments such as Pfizer's Paxlovid are expected to remain effective and so EU states should stock up on them for high-risk patients, the EMA said.
Monoclonal antibodies had been shown to reduce the risk of hospitalisation and death by up to 80 percent, but they have lost their edge as the virus has mutated.
The World Health Organisation in September recommended against using Xevudy and Ronapreve because they had stopped being effective against new variants.
Covid has kept evolving since it emerged in China at the end of 2019 to cause a global pandemic that is now waning.
While previous "variants of concern" like Alpha and Delta eventually petered out, Omicron and its sub-lineages have dominated throughout 2022 and look set to continue into 2023.
With inputs from AFP