Top seed Fognini out of Sardinia tennis with coronavirus
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"Guys, I have to tell you that this morning I tested positive for Covid-19," the 33-year-old said on Instagram.
"The symptoms are very mild, a little cough and fever, headache ... but unfortunately this bad news has arrived.
"I'm already in isolation and I'm convinced that I will recover very soon. I hug you all."
Fognini, 33, had a first-round bye and was set to open in the second round against Spain's Roberto Carballes Baena in the tournament played on clay on the Italian island of Sardinia.
The world number 16 was replaced by Croatian Danilo Petrovic.
Fognini and doubles partner Lorenzo Musetti lost their last-16 tie to fellow Italians Lorenzo Sonego and Andrea Vavassori on Tuesday, following a 15-13 third-set tiebreak in a match lasting more than two hours.
"All the people with whom Fognini was in direct contact were placed in preventive isolation and subjected to new swabs," the Italian tennis federation said in a statement.
Fognini, who won the Monte Carlo Masters last year, was out for six months this year following surgery to both ankles.