Harrowing video of children after Kabul attack shocks Afghanistan
At least two people were killed and five others wounded in the explosion, which appeared to target security forces in the Afghan capital, said Kabul police spokesman Ferdaws Faramarz.
The two children -- one of them covered in blood -- can be heard screaming. At one point, one says, "Mother, get up!"
"Unbearable to watch this mother & her children like this," wrote one Twitter user, Ejaz Malikzada.
"How could those who commit this justifies their action to their own souls while you see kids crying for their injured mother? This needs to STOP," said Fawzia Koofi, a member of the government's peace team negotiating with the Taliban.
No group claimed responsibility for the attack, but Afghan security forces are regularly targeted by the Taliban.
The Taliban denied any involvement.
Kabul, along with urban areas across Afghanistan, have been rocked by frequent explosions on an almost daily basis amid the fraught peace talks between the government and the Taliban.
The surge in violence has led US President Joe Biden's administration to launch a review of a deal signed between Washington and the Taliban last year.
That agreement paved the way for the withdrawal of all US troops in the coming months and kickstarted the peace talks between the Kabul government and the insurgents.
Biden is reviewing whether to stick to a looming May 1 deadline to withdraw the remaining 2,500 US troops or risk a bloody backlash from the insurgents by staying.