Fast bowler Kagiso Rabada took two wickets for just eight runs as he led a South African fightback against Pakistan in their first Test in Karachi Tuesday.

Pakistan were in trouble at 33 for four at the close of play, having bowled out the visitors for 220 -- their second-lowest total in the country.

Fourteen wickets fell on the brownish National Stadium pitch, which had been expected to take spin from day one. South Africa were well placed at 108-2 soon after lunch, but lost their last eight wickets for just 112 runs -- barely managing to overhaul their lowest total in Pakistan, the 214 made at Faisalabad in 1997.

Spinners Yasir Shah (3-54), debutant Nauman Ali (2-38) and pacer Shaheen Shah Afridi (2-49) did the damage.

But then Rabada paid the hosts back with interest, bowling Abid Ali (four) in his third over and then getting debutant Imran Butt (nine) caught at leg-slip off a rising delivery. He now has 199 wickets from 44 Tests.

Babar Azam, leading Pakistan for the first time in a Test, fell lbw to spinner Keshav Maharaj for seven before night watchman Shaheen was bowled by Anrich Nortje without scoring.

At the close, Azhar Ali and Fawad Alam were unbeaten on five each - with Pakistan trailing by 187 runs with six wickets intact.

Earlier, opener Dean Elgar top-scored for South Africa with 58, while George Linde (35) and Rabada (21 not out) were other notable contributors. Elgar struck his 16th Test half-century -- laced with nine boundaries -- before he edged Nauman into the hands of Azam at slip.

Elgar and Faf du Plessis (23) had steadied the innings during their 45-run stand for the third wicket after Aiden Markram (13) and Rassie van der Dussen (17) were dismissed in the first session.

Both Pakistan and South Africa entered the Test with two spinners and three pace bowlers. The two-match series marks the first tour by South Africa to Pakistan in 14 years, a positive step for the revival of international cricket in the host country.

A deadly attack on Sri Lanka's team in 2009 froze international tours to Pakistan before their gradual resumption in recent years.