Assad says Western criticism of Syria vote has 'zero value'
Voting is being held only in government-controlled areas and the United States and the European Union said Tuesday the election was "neither free nor fair."
"This fraudulent election does not represent any progress towards a political settlement," they said in a joint statement.
Assad and his British-born wife Asma both cast their votes in the suburb of Douma, a key rebel stronghold before it was retaken by government forces in 2018.
The president wore a dark blue suit, his wife a light grey dress.
Other voters surrounded Assad at the polling station chanting: "With our blood and with our souls, we sacrifice our lives for you, Bashar."
"As a state, we do not accept this behaviour," Assad said.
The vote is the second election since the start of a decade-long civil war, that has killed more than 388,000 people and displaced half the pre-war population.
With opponents abroad barred from standing and no voting in the swathes of territory outside government control, Assad faces two virtually unknown challengers.