New Zealand's Southee joins elite 300 club
He is only the third New Zealander to reach the milestone, behind Richard Hadlee who took 431 scalps from 86 Tests and Daniel Vettori with 361 wickets in 112 matches.
Globally, the 32-year-old right-armer is only the 34th bowler to reach 300 wickets in the history of Test cricket.
He has taken four wickets so far in the first Test against Pakistan who are 37 for three in their second innings chasing a target of 373.
Southee said before the Test that reaching the 300 milestone was not a target but "when you play for long enough those things happen."
His best performance was seven for 64 in Bangalore eight years ago, the most successful return for a New Zealand bowler in India.