First monkeypox case reported in Japan
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She said the man had been hospitalised in Tokyo, without giving further details.
On Saturday, the World Health Organization declared the monkeypox outbreak a global health emergency -- the highest alarm it can sound.
Monkeypox has affected more than 16,800 people in 74 countries, according to a tally by the US Centers for Disease Control and Prevention (CDC) published on July 22.
Ninety-five percent of cases have been transmitted through sexual activity, according to a study of 528 people in 16 countries published in the New England Journal of Medicine -- the largest research to date.
WHO chief Tedros Adhanom Ghebreyesus has previously expressed concern that stigma and scapegoating could make the outbreak harder to track.
A Danish drugmaker of smallpox vaccines said on Monday the European Commission has approved its jab for use against monkeypox.
Health Minister Shigeyuki Goto said in May that the vaccines are "produced and stockpiled in Japan from a counter-terrorism perspective" to prepare the country to respond to possible attacks with a viral agent.