Scientists grow 'model' human embryos from stem cells
Scientists have developed a human embryo "blueprint" using human stem cells, in a breakthrough that could provide vital insight into the early stages of infant development, new research showed Thursday.
The layout of humans -- known as the body plan -- happens through a process known as gastrulation, where three distinct layers of cells are formed in the embryo that will later give rise to the body's three main systems: nervous, musculoskeletal and digestive.
The team behind the study, published in Nature, said their model resembles an embryo between 18 and 21 days old, around the same time as gastrulation occurs.
Many birth defects happen during this period, and a better understanding of gastrulation could aid our understanding of issues such as infertility, miscarriage and genetic disorders, the researchers said.
"It's exciting to witness the developmental processes that until now have been hidden from view -- and from study."
Nevertheless they were able to observe around 72 hours of the models' development and identify clear signs of the events that lead to the formation of muscles, bone and cartilage.
Jeremy Green, a professor of developmental biology at King's College London, said the study was a "fantastic window" into the early formation of the human body.
"(It) highlights the amazing power of self-organisation of cells and tissues given the right conditions," added Green, who was not involved in the research.