Two dead, several wounded in attack on Afghan police base
The complex attack in the city of Khost was launched early in the morning, and has wounded 14 security personnel and nine civilians.
A gun battle near the base was ongoing, an AFP correspondent reported.
After the blast a group of attackers tried to enter the base compound resulting in a gun battle with security forces, Afghanistan's interior ministry spokesman Tariq Arian told reporters.
Four attackers have been killed while two more were still fighting, Arian said.
Khost provincial health official Gul Mohammad said women and children were among the wounded.
Violence has surged across Afghanistan in recent weeks even as the Taliban and Afghan government remain engaged in peace talks to end the country's long-running conflict.
Afghan and US officials have repeatedly warned that the rising bloodshed was threatening the peace talks being held in Qatar since last month.
Most attacks by the Taliban have targeted Afghan security forces, although scores of civilians have also been killed.